So, here’s the deal: yes, your car’s air-conditioning can, “run out,” of Freon™, but it may not be in the way you think. Freon is contained within your vehicle’s AC system, as in completely confined within, so Freon’s loss isn’t through consumption but through leaks that eventually develop within hoses and connections. No surprise, under your car’s hood is a hostile environment, so over the years of extreme temperatures, weather, road debris, as well as the shaking and shimmying of hundreds and thousands of miles driven, seals can dry up and fail.